Campbell C, Dikiy S, Bhattarai SK, Chinen T, Matheis F, Calafiore M, Hoyos B, Hanash A, Mucida D, Bucci V, Rudensky AY. Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance. Immunity. 48:1245-1257,2018

Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY.An essential role for the IL-2 receptor in Treg cell function.Nat Immunol.  17:1322-1333, 2016

Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY.Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.Cell. 158:749-63, 2014

 Josefowicz S, Niec R, Kim HY, Treuting P, Chinen T, Umetsu DT, Rudensky AY. Extrathymically generated regulatory T cells control mucosal Th2 inflammation. Nature.  482:395-9, 2012

Chinen T, Komai K, Muto G, Morita R, Inoue N, Yoshida H, Sekiya T, Nakamura K, Yoshimura A. Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance. Nat Commun. 2:190, 2011

Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Chinen T, Yoshimura A. SOCS1 is essential for Treg cell functions by preventing loss of Foxp3 expression as well as IFN-g and IL-17A production. J Exp Med. 208:2055-67, 2011

Chinen T, Volchkov PY, Chervonsky AV, Rudensky AY. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. J Exp Med.  207:2323-30, 2010

Ichiyama K, Yoshida H, Wakabayashi Y, Chinen T, Saeki K, Takaesu G, Hori S, Yoshimura A, Kobayashi T. Foxp3 inhibits RORgt-mediated IL-17A mRNA transcription through direct interaction with RORgt. J Biol Chem. 283:17003-8, 2008

Ogata H, Kobayashi T, Chinen T, Takaki H, Sanada T, Minoda Y, Koga K, Takaesu G, Yoshimura A. Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. Gastroenterology. 131:179-93, 2006 

Chinen T, Kobayashi T, Ogata H, Takaesu G, Takaki H, Yagita H, Nawata H, Yoshimura A.  SOCS1 regulates inflammatory bowel disease in which both IFNg and IL-4 are involved. Gastroenterology. 130:373-88, 2006

Hanada T, Kobayashi T, Chinen T, Saeki K, Takaki H, Koga K, Minoda Y, Sanada T, Yoshimura A. IFNg-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. J Exp Med. 203:1391-7, 2006

Ogata H, Chinen T, Yoshida T, Kinjyo I, Takaesu G, Shiraishi H, Iida M, Kobayashi T, Yoshimura A. Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-b1 production. Oncogene. 25:2520-30, 2006

Chinen T, Misawa T, Yao T, Nasu T, Yoshida K, Kubo S, Toyoshima S, Sakaguchi T, Harada N. Pedunculated cap polyps preceding the development of cap polyposis: case report. Gastrointest Endosc. 61:338-40, 2005

Chinen T, Misawa T, Yoshida K, Nasu T, Kubo S, Toyoshima S, Yao T, Harada N. Esophageal submucosal gland duct adenoma. Gastrointest Endos. 60:798-9, 2004

Inagaki-Ohara K, Chinen T, Matsuzaki G, Sasaki A, Sakamoto Y, Hiromatsu K, Nawa Y, Yoshimura A. Mucosal T cells bearing TCRgd play a protective role in intestinal inflammation. J Immunol. 173:1390-8, 2004

Yasukawa H, Ohishi M, Mori H, Murakami M, Chinen T, Takeda K, Akira S, Hoshijima M, Hirano T, Yoshimura A. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol. 4:551-6, 2003