研究室紹介
Our Laboratories
研究室紹介
Our Laboratories
田中 義将 業績
原著論文
Bussaka K, Tanaka Y, Kondoh K, Nakajima KI, Chinen T, Bai X, Minoda Y, Ikeda H, Inamura K, Takeshima T, Ogino H, Ihara E, Minokoshi Y, Ogawa Y: Barrington's nucleus: A pontine defecation brain area exhibiting prompt and delayed defecation responses. Cell Mol Gastroenterol Hepatol 20(1): 101635, 2026
Tsuru H, Ihara E, Muta K, Mittal RK, Zifan A, Wada M, Fukuya H, Hata Y, Bai X, Tanaka Y, Minoda Y, Esaki M, Ogino H, Chinen T, Ogawa Y: Striated muscle contractility and distal esophageal distensibility define novel subtypes of functional dysphagia. Clin Gastroenterol Hepatol 2025
Nishioka K, Ogino H, Ihara E, Chinen T, Kimura Y, Esaki M, Bai X, Minoda Y, Tanaka Y, Wada M, Hata Y, Ambrosini YM, Ogawa Y: Importance of rectal over colon status in ulcerative colitis remission: The role of microinflammation and mucosal barrier dysfunction in relapse. J Gastroenterol 60(4): 416-429, 2025
Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y: Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc 37(5): 512-520, 2025
Kimura Y, Minoda Y, Ihara E, Ogino H, Inamura K, Bai X, Tanaka Y, Chinen T, Sakamoto R, Nakayama J, Watanabe K, Kimura I, Ogawa Y: An endoscopic real-time, in situ assessment of intestinal permeability in type 2 diabetes: Links to microbiota and hyperglycemia. J Gastroenterol 2025
Hayashi Y, Ogino H, Minoda Y, Tanaka Y, Hata Y, Kubokawa M, Sakisaka S, Haraguchi K, Fukuda SI, Itaba S, Yoshimura D, Takahashi S, Tanaka M, Kubo H, Somada S, Ihara E, Ogawa Y: Endoscopic resection of rectal neuroendocrine tumors: Zero disease-related deaths during a 10-year follow-up period. BMC Gastroenterol 25(1): 155, 2025
Esaki M, Sumida Y, Maehara K, Yamaguchi D, Nishioka K, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nomura T, Mizuta Y, Ishida S, Fujimoto S, Kimura S, Tanaka Y, Hata K, Shiga N, Iwasa T, Kimura Y, Nakamura N, Suzuki Y, Minoda Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Tagawa K, Ogawa Y: Spray and forced coagulation mode endoscopic submucosal dissection for early gastric neoplasms: A multicenter randomized controlled trial. Am J Gastroenterol 120(11): 2538-2547, 2025
Esaki M, Maehara K, Sumida Y, Minoda Y, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nakamura N, Suzuki Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Ogawa Y: Feasibility of traction band-assisted endoscopic closure for mucosal defects after colorectal endoscopic submucosal dissection: A multicenter prospective single-arm pilot study. Endoscopy 57(9): 1016-1022, 2025
Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y. Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc. 2024
Igarashi-Hisayoshi Y, Ihara E, Bai X, Tanaka Y, Ogino H, Chinen T, et al. Protective role of M(3) muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury. J Mol Med (Berl). 2024;102(9):1175-86.
Minoda Y, Ogino H, Sumida Y, Osoegawa T, Itaba S, Hashimoto N, Esaki M, Kitagawa Y, Yodoe K, Iboshi Y, Matsuguchi T, Tadokoro M, Chaen T, Kubo H, Kubokawa M, Harada N, Nishizima K, Fujii H, Hata Y, Tanaka Y, Ihara E, Ogawa Y. Is a small-caliber or large-caliber endoscope more suitable for colonic self-expandable metallic stent placement? A randomized controlled study. Therap Adv in Gastroenterol 2022;15:17562848211065331.
Igarashi HY, Ihara E, Bai X, Higashi C, Ikeda H, Tanaka Y, Hirano M, Ogino H, Chinen T, Taguchi Y, Ogawa Y: Determination of region-specific roles of the M3 muscarinic acetylcholine receptor in gastrointestinal motility. Dig Dis Sci 68(2): 439-450,2023
Minoda Y, Esaki M, Ihara E, Nagatomo S, Nishioka K, Fujimori N, Ogino H, Bai X, Tanaka Y, Chinen T, Hu Q, Ota M, Umekita S, Yamamoto H, Ogawa Y: Auxilliary diagnosis of subepithelial lesions by impedance measurement during endoscopic ultrasound fine-needle aspiration biopsy. Gastrointest Endosc 97(5): 977-984, 2023
Ihara E*, Ogino H*, Muta K, Hamada S, Wada M, Hata Y, Ikeda H, Bai X, Minoda Y, Esaki M, Tanaka Y, Chinen T and Ogawa Y. The treatment effects of acotiamide in esophagogastric outflow obstruction: A prospective longitudinal observational study. Esophagus 2021 In press. *, These authors contributed equally to this work.
Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y. Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. Eur J Pharmacol 2021 In press.
Nishioka K, Ogino H, Chinen T, Ihara E, Tanaka Y, Nakamura K, Ogawa Y. Mucosal IL23A expression predicts the response to Ustekinumub in inflammatory bowel disease. J Gastroenterol 2021 In press. Corresponding author
Nishihara Y, Ogino H, Tanaka M, Ihara E, Fukaura K, Nishioka K, Chinen T, Tanaka Y, Nakayama J, Kang Dongchon and Ogawa Y. Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis. Sci Rep 2021 Jul;11(1):13732.
Muta K, Ihara E, Hamada S, Ikeda H, Wada M, Hata Y, Bai X, Nishihara Y, Tanaka Y, Ogino H, Ogawa Y. Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallow. Sci Rep 2021 Apr12;11(1):7898.
Okuno H, Ogino H, Ihara E, Nishioka K, Tanaka Y, Chinen T, Kohjima M, Oono T, Tanaka M, Goya T, Fujimori N, Iboshi Y, Gotoda T, Ogawa Y. Discriminant equation using mucosally expressed cytokines and transcription factor for making definite diagnosis of inflammatory bowel disease unclassified.
BMC Gastroenterology 2020 In press.
Hamada S, Ihara E, Muta K, Wada M, Hata Y, Ikeda H, Tanaka Y, Ogino H, Chinen T and Ogawa Y. Onigiri esophagography as a screening test for esophageal motility disorders. J Neurogastroenterol Motil 2021;28(1):43-52
Hamada S, Ihara E, Ikeda H, Muta K, Ogino H, Chinen T, Tanaka Y, Ogawa Y. Clinical characterization of vonoprazan-refractory gastroesophageal reflux disease. Digestion 2021;102(2):197-204.
Tsuru H, Ihara E, Muta K, Mittal RK, Zifan A, Wada M, Fukuya H, Hata Y, Bai X, Tanaka Y, Minoda Y, Esaki M, Ogino H, Chinen T, Ogawa Y: Striated muscle contractility and distal esophageal distensibility define novel subtypes of functional dysphagia. Clin Gastroenterol Hepatol 2025
Nishioka K, Ogino H, Ihara E, Chinen T, Kimura Y, Esaki M, Bai X, Minoda Y, Tanaka Y, Wada M, Hata Y, Ambrosini YM, Ogawa Y: Importance of rectal over colon status in ulcerative colitis remission: The role of microinflammation and mucosal barrier dysfunction in relapse. J Gastroenterol 60(4): 416-429, 2025
Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y: Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc 37(5): 512-520, 2025
Kimura Y, Minoda Y, Ihara E, Ogino H, Inamura K, Bai X, Tanaka Y, Chinen T, Sakamoto R, Nakayama J, Watanabe K, Kimura I, Ogawa Y: An endoscopic real-time, in situ assessment of intestinal permeability in type 2 diabetes: Links to microbiota and hyperglycemia. J Gastroenterol 2025
Hayashi Y, Ogino H, Minoda Y, Tanaka Y, Hata Y, Kubokawa M, Sakisaka S, Haraguchi K, Fukuda SI, Itaba S, Yoshimura D, Takahashi S, Tanaka M, Kubo H, Somada S, Ihara E, Ogawa Y: Endoscopic resection of rectal neuroendocrine tumors: Zero disease-related deaths during a 10-year follow-up period. BMC Gastroenterol 25(1): 155, 2025
Esaki M, Sumida Y, Maehara K, Yamaguchi D, Nishioka K, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nomura T, Mizuta Y, Ishida S, Fujimoto S, Kimura S, Tanaka Y, Hata K, Shiga N, Iwasa T, Kimura Y, Nakamura N, Suzuki Y, Minoda Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Tagawa K, Ogawa Y: Spray and forced coagulation mode endoscopic submucosal dissection for early gastric neoplasms: A multicenter randomized controlled trial. Am J Gastroenterol 120(11): 2538-2547, 2025
Esaki M, Maehara K, Sumida Y, Minoda Y, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nakamura N, Suzuki Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Ogawa Y: Feasibility of traction band-assisted endoscopic closure for mucosal defects after colorectal endoscopic submucosal dissection: A multicenter prospective single-arm pilot study. Endoscopy 57(9): 1016-1022, 2025
Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y. Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc. 2024
Igarashi-Hisayoshi Y, Ihara E, Bai X, Tanaka Y, Ogino H, Chinen T, et al. Protective role of M(3) muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury. J Mol Med (Berl). 2024;102(9):1175-86.
Minoda Y, Ogino H, Sumida Y, Osoegawa T, Itaba S, Hashimoto N, Esaki M, Kitagawa Y, Yodoe K, Iboshi Y, Matsuguchi T, Tadokoro M, Chaen T, Kubo H, Kubokawa M, Harada N, Nishizima K, Fujii H, Hata Y, Tanaka Y, Ihara E, Ogawa Y. Is a small-caliber or large-caliber endoscope more suitable for colonic self-expandable metallic stent placement? A randomized controlled study. Therap Adv in Gastroenterol 2022;15:17562848211065331.
Igarashi HY, Ihara E, Bai X, Higashi C, Ikeda H, Tanaka Y, Hirano M, Ogino H, Chinen T, Taguchi Y, Ogawa Y: Determination of region-specific roles of the M3 muscarinic acetylcholine receptor in gastrointestinal motility. Dig Dis Sci 68(2): 439-450,2023
Minoda Y, Esaki M, Ihara E, Nagatomo S, Nishioka K, Fujimori N, Ogino H, Bai X, Tanaka Y, Chinen T, Hu Q, Ota M, Umekita S, Yamamoto H, Ogawa Y: Auxilliary diagnosis of subepithelial lesions by impedance measurement during endoscopic ultrasound fine-needle aspiration biopsy. Gastrointest Endosc 97(5): 977-984, 2023
Ihara E*, Ogino H*, Muta K, Hamada S, Wada M, Hata Y, Ikeda H, Bai X, Minoda Y, Esaki M, Tanaka Y, Chinen T and Ogawa Y. The treatment effects of acotiamide in esophagogastric outflow obstruction: A prospective longitudinal observational study. Esophagus 2021 In press. *, These authors contributed equally to this work.
Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y. Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. Eur J Pharmacol 2021 In press.
Nishioka K, Ogino H, Chinen T, Ihara E, Tanaka Y, Nakamura K, Ogawa Y. Mucosal IL23A expression predicts the response to Ustekinumub in inflammatory bowel disease. J Gastroenterol 2021 In press. Corresponding author
Nishihara Y, Ogino H, Tanaka M, Ihara E, Fukaura K, Nishioka K, Chinen T, Tanaka Y, Nakayama J, Kang Dongchon and Ogawa Y. Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis. Sci Rep 2021 Jul;11(1):13732.
Muta K, Ihara E, Hamada S, Ikeda H, Wada M, Hata Y, Bai X, Nishihara Y, Tanaka Y, Ogino H, Ogawa Y. Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallow. Sci Rep 2021 Apr12;11(1):7898.
Okuno H, Ogino H, Ihara E, Nishioka K, Tanaka Y, Chinen T, Kohjima M, Oono T, Tanaka M, Goya T, Fujimori N, Iboshi Y, Gotoda T, Ogawa Y. Discriminant equation using mucosally expressed cytokines and transcription factor for making definite diagnosis of inflammatory bowel disease unclassified.
BMC Gastroenterology 2020 In press.
Hamada S, Ihara E, Muta K, Wada M, Hata Y, Ikeda H, Tanaka Y, Ogino H, Chinen T and Ogawa Y. Onigiri esophagography as a screening test for esophageal motility disorders. J Neurogastroenterol Motil 2021;28(1):43-52
Hamada S, Ihara E, Ikeda H, Muta K, Ogino H, Chinen T, Tanaka Y, Ogawa Y. Clinical characterization of vonoprazan-refractory gastroesophageal reflux disease. Digestion 2021;102(2):197-204.
総説
伊原 栄吉，田中 義将，竹島 翼，白 暁鵬，蓑田 洋介，荻野 治栄:
【慢性便秘症の診療のポイント】慢性便秘症の病態 臨床消化器内科 40(3): 291-297, 2025
荻野 治栄，田中 義将，伊原 栄吉:
【薬剤師の情報福袋 新薬,診療GL,etc詰め合わせ】Pick Up! 注目の診療ガイドライン 新薬続々,便通異常症診 療ガイドライン2023 機能性便秘症と機能性下痢症 薬局 76(1): 36-40, 2025
鈴木 祐輔，荻野 治栄，蓑田 洋介，田中 義将，伊原 栄吉:
【「胃と腸」式 読影問題集2025-症例から学ぶ診断のポイント】咽頭・食道 13 Cases Case 13 胃と腸 60(10): 1262-1266, 2025
Bai X, Ihara E, Tanaka Y, Minoda Y, Wada M, Hata Y, Esaki M, Ogino H, Chinen T, Ogawa Y: The interplay of gut microbiota and intestinal motility in gastrointestinal function. J Smooth Muscle Res 6151-58, 2025
Bai X, Ihara E, Tanaka Y, Minoda Y, Wada M, Hata Y, Esaki M, Ogino H, Chinen T, Ogawa Y: From bench to bedside: The role of gastrointestinal stem cells in health and disease. Inflamm Regen 45(1): 15, 2025
伊原 栄吉，田中 義将，荻野 治栄:
【高齢者の消化器疾患-最新の診断と治療-】高齢者における慢性便秘症の診断と治療
日本臨床 81(2): 242-249, 2023
田中 義将，荻野 治栄，伊原 栄吉:
【機能性消化管疾患-過敏性腸症候群と慢性便秘症診療の最前線】過敏性腸症候群の病態に応じた段階的治療戦略
日本消化器病学会雑誌 120(3): 218-230, 2023
伊原 栄吉, 水流 大尭, 和田 将史，畑 佳孝，白 暁鵬，田中 義将，蓑田 洋介，江崎 充，荻野 治栄:
【GERDを極める】非びらん性胃食道逆流症の病態と鑑別診断
消化器内視鏡 35(5): 607-614, 2023
荻野 治栄, 田中 義将, 知念 孝敏, 伊原 栄吉
【特殊状況下でのIBD診療を身につける!】担癌患者のIBD診療を身につけるIBD research 17:20-27、2023
畑佳孝, 伊原栄吉, 和田将史, 水流大尭, 江崎充, 蓑田洋介, 白暁鵬, 田中義将, 荻野治栄
特集I 胃食道逆流症（GERD）ガイドラインの改正をめぐって：Barrett食道の発癌予防の諸問題. 消化器・肝臓内科, 2021;10(5):551-560.(Editorial) Esaki M, Minoda Y, Ihara E. In living color: Linked color imaging for the detection of early gastric cancer. Dig Dis Sci.doi.org/10.1007/s10620-021-07235-4.
荻野 治栄，田中 義将，知念 孝敏，小森 圭司，伊原 栄吉，小川 佳宏
【これだけは知っておきたい消化管疾患の診断・治療】消化管における慢性炎症
消化器クリニカルアップデート 2, 24-28, 2020
荻野 治栄，田中 義将，知念 孝敏，小森 圭司，伊原 栄吉，小川 佳宏
【これだけは知っておきたい消化管疾患の診断・治療】消化管における慢性炎症．消化器クリニカルアップデート 2, 24-28, 2020
【慢性便秘症の診療のポイント】慢性便秘症の病態 臨床消化器内科 40(3): 291-297, 2025
荻野 治栄，田中 義将，伊原 栄吉:
【薬剤師の情報福袋 新薬,診療GL,etc詰め合わせ】Pick Up! 注目の診療ガイドライン 新薬続々,便通異常症診 療ガイドライン2023 機能性便秘症と機能性下痢症 薬局 76(1): 36-40, 2025
鈴木 祐輔，荻野 治栄，蓑田 洋介，田中 義将，伊原 栄吉:
【「胃と腸」式 読影問題集2025-症例から学ぶ診断のポイント】咽頭・食道 13 Cases Case 13 胃と腸 60(10): 1262-1266, 2025
Bai X, Ihara E, Tanaka Y, Minoda Y, Wada M, Hata Y, Esaki M, Ogino H, Chinen T, Ogawa Y: The interplay of gut microbiota and intestinal motility in gastrointestinal function. J Smooth Muscle Res 6151-58, 2025
Bai X, Ihara E, Tanaka Y, Minoda Y, Wada M, Hata Y, Esaki M, Ogino H, Chinen T, Ogawa Y: From bench to bedside: The role of gastrointestinal stem cells in health and disease. Inflamm Regen 45(1): 15, 2025
伊原 栄吉，田中 義将，荻野 治栄:
【高齢者の消化器疾患-最新の診断と治療-】高齢者における慢性便秘症の診断と治療
日本臨床 81(2): 242-249, 2023
田中 義将，荻野 治栄，伊原 栄吉:
【機能性消化管疾患-過敏性腸症候群と慢性便秘症診療の最前線】過敏性腸症候群の病態に応じた段階的治療戦略
日本消化器病学会雑誌 120(3): 218-230, 2023
伊原 栄吉, 水流 大尭, 和田 将史，畑 佳孝，白 暁鵬，田中 義将，蓑田 洋介，江崎 充，荻野 治栄:
【GERDを極める】非びらん性胃食道逆流症の病態と鑑別診断
消化器内視鏡 35(5): 607-614, 2023
荻野 治栄, 田中 義将, 知念 孝敏, 伊原 栄吉
【特殊状況下でのIBD診療を身につける!】担癌患者のIBD診療を身につけるIBD research 17:20-27、2023
畑佳孝, 伊原栄吉, 和田将史, 水流大尭, 江崎充, 蓑田洋介, 白暁鵬, 田中義将, 荻野治栄
特集I 胃食道逆流症（GERD）ガイドラインの改正をめぐって：Barrett食道の発癌予防の諸問題. 消化器・肝臓内科, 2021;10(5):551-560.(Editorial) Esaki M, Minoda Y, Ihara E. In living color: Linked color imaging for the detection of early gastric cancer. Dig Dis Sci.doi.org/10.1007/s10620-021-07235-4.
荻野 治栄，田中 義将，知念 孝敏，小森 圭司，伊原 栄吉，小川 佳宏
【これだけは知っておきたい消化管疾患の診断・治療】消化管における慢性炎症
消化器クリニカルアップデート 2, 24-28, 2020
荻野 治栄，田中 義将，知念 孝敏，小森 圭司，伊原 栄吉，小川 佳宏
【これだけは知っておきたい消化管疾患の診断・治療】消化管における慢性炎症．消化器クリニカルアップデート 2, 24-28, 2020