九州大学大学院医学研究院 病態制御内学科(第三内科) 九州大学大学院医学研究院 病態制御内学科(第三内科)

Our Laboratories

総合消化器研究室 消化器グループ

原著論文

Bussaka K, Tanaka Y, Kondoh K, Nakajima KI, Chinen T, Bai X, Minoda Y, Ikeda H, Inamura K, Takeshima T, Ogino H, Ihara E, Minokoshi Y, Ogawa Y: Barrington's nucleus: A pontine defecation brain area exhibiting prompt and delayed defecation responses. Cell Mol Gastroenterol Hepatol 20(1): 101635, 2026

Watanabe K, Fukuda S, Kubota D, Yamamichi N, Takahashi Y, Watanabe Y, Adachi K, Ishimura N, Koike T, Sugawara H, Asanuma K, Abe Y, Kon T, Ihara E, Haraguchi K, Otsuka Y, Yoshimura R, Iwaya Y, Okamura T, Manabe N, Horiuchi A, Matsumoto M, Onochi K, Takahashi S, Yoshida T, Shimodaira Y, Iijima K: Potentially causal associations between extensive gastric atrophy and esophageal squamous cell carcinoma: A nationwide retrospective cohort study in japan. Dig Endosc 37(12): 1332-1339, 2025

Umekita S, Kiyozawa D, Honma H, Kohashi K, Taniguchi Y, Kawatoko S, Sasaki T, Ihara E, Oki E, Nakamura M, Ogawa Y, Oda Y: Clinicopathological significance of jak2, stat3, and stat4 expression in patients with gastric solid-type poorly differentiated adenocarcinoma: A retrospective study. Gastric Cancer 28(3): 455-464, 2025

Tsuru H, Ihara E, Muta K, Mittal RK, Zifan A, Wada M, Fukuya H, Hata Y, Bai X, Tanaka Y, Minoda Y, Esaki M, Ogino H, Chinen T, Ogawa Y: Striated muscle contractility and distal esophageal distensibility define novel subtypes of functional dysphagia. Clin Gastroenterol Hepatol 2025

Sawada A, Hoshikawa Y, Hosaka H, Saito M, Tsuru H, Kato S, Ihara E, Koike T, Uraoka T, Kasugai K, Iwakiri K, Sifrim D, Pandolfino JE, Taft TH, Fujiwara Y, Japan ESG: Validation of the japanese version of the esophageal hypervigilance and anxiety scale for esophageal symptoms. J Gastroenterol 60(3): 265-274, 2025

Nishioka K, Ogino H, Ihara E, Chinen T, Kimura Y, Esaki M, Bai X, Minoda Y, Tanaka Y, Wada M, Hata Y, Ambrosini YM, Ogawa Y: Importance of rectal over colon status in ulcerative colitis remission: The role of microinflammation and mucosal barrier dysfunction in relapse. J Gastroenterol 60(4): 416-429, 2025

Miura T, Ishii H, Hata Y, Takigawa-Imamura H, Sugihara K, Ei SI, Bai X, Ihara E, Ogawa Y: A mathematical model of human oesophageal motility function. R Soc Open Sci 12(8): 250491, 2025

Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y: Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc 37(5): 512-520, 2025

Kimura Y, Minoda Y, Ihara E, Ogino H, Inamura K, Bai X, Tanaka Y, Chinen T, Sakamoto R, Nakayama J, Watanabe K, Kimura I, Ogawa Y: An endoscopic real-time, in situ assessment of intestinal permeability in type 2 diabetes: Links to microbiota and hyperglycemia. J Gastroenterol 2025

Hayashi Y, Ogino H, Minoda Y, Tanaka Y, Hata Y, Kubokawa M, Sakisaka S, Haraguchi K, Fukuda SI, Itaba S, Yoshimura D, Takahashi S, Tanaka M, Kubo H, Somada S, Ihara E, Ogawa Y: Endoscopic resection of rectal neuroendocrine tumors: Zero disease-related deaths during a 10-year follow-up period. BMC Gastroenterol 25(1): 155, 2025

Fukuya H, Ihara E, Iboshi Y, Sumida Y, Yoshimura D, Hamada S, Sasaki T, Ohkubo A, Itonaga S, Homma H, Okitsu R, Ohno A, Esaki M, Harada N: Clinical feasibility of gastric endoscopic submucosal dissection in patients on glucocorticoids or immunomodulators: Propensity-score-matched study. Endosc Int Open 13a27331229, 2025

Fukuda S, Watanabe K, Kubota D, Yamamichi N, Takahashi Y, Watanabe Y, Adachi K, Ishimura N, Koike T, Sugawara H, Asanuma K, Abe Y, Kon T, Ihara E, Haraguchi K, Otsuka Y, Yoshimura R, Iwaya Y, Okamura T, Manabe N, Horiuchi A, Matsumoto M, Onochi K, Takahashi S, Yoshida T, Shimodaira Y, Iijima K: Age distribution and risk factors for barrett's esophagus by sex at health check-up settings in japan. J Gastroenterol 60(7): 820-828, 2025

Esaki M, Sumida Y, Maehara K, Yamaguchi D, Nishioka K, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nomura T, Mizuta Y, Ishida S, Fujimoto S, Kimura S, Tanaka Y, Hata K, Shiga N, Iwasa T, Kimura Y, Nakamura N, Suzuki Y, Minoda Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Tagawa K, Ogawa Y: Spray and forced coagulation mode endoscopic submucosal dissection for early gastric neoplasms: A multicenter randomized controlled trial. Am J Gastroenterol 120(11): 2538-2547, 2025

Esaki M, Maehara K, Sumida Y, Minoda Y, Homma H, Inada T, Shiotsuki K, Fukuda SI, Akiho H, Nakamura N, Suzuki Y, Bai X, Tanaka Y, Hata Y, Ogino H, Chinen T, Ihara E, Ogawa Y: Feasibility of traction band-assisted endoscopic closure for mucosal defects after colorectal endoscopic submucosal dissection: A multicenter prospective single-arm pilot study. Endoscopy 57(9): 1016-1022, 2025

Umekita S, Kiyozawa D, Kohashi K, Kawatoko S, Sasaki T, Ihara E, et al. Clinicopathological significance of microsatellite instability and immune escape mechanism in patients with gastric solid-type poorly differentiated adenocarcinoma. Gastric Cancer. 2024;27(3):484-94. 

 Nishioka K, Ogino H, Ihara E, Chinen T, Kimura Y, Esaki M, et al. Importance of rectal over colon status in ulcerative colitis remission: the role of microinflammation and mucosal barrier dysfunction in relapse. J Gastroenterol. 2024.

Ikeda H, Ihara E, Takeya K, Mukai K, Onimaru M, Ouchida K, et al. The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia. J Gastroenterol. 2024;59(5):361-75. 

Igarashi-Hisayoshi Y, Ihara E, Bai X, Tanaka Y, Ogino H, Chinen T, et al. Protective role of M(3) muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury. J Mol Med (Berl). 2024;102(9):1175-86. 

Wada M, Minoda Y, Ihara E, Tsuru H, Hata Y, Nagatomo S, et al. Development of a new endoscopy system to visualize bilirubin for the diagnosis of duodenogastroesophageal reflux. Dig Endosc. 2024;36(8):904-14. 

Minoda Y, Suzuki Y, Ogino H, Nagatomo S, Bai X, Esaki M, Wada M, Tanaka Y, Hata Y, Fujimori N, Umekita S, Tsurumaru D, Ota M, Oki E, Ihara E, Ogawa Y. Traction-assisted endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions: Randomized controlled trial (with video). Dig Endosc. 2024 

Esaki M, Ihara E, Manabe N, Kawami N, Iwakiri K, Akiyama J, Kuribayashi S, Uraoka T, Ogino H, Chinen T, Misumi A, Watanabe H, Suzuki M, Kishimoto J, Ogawa Y: Evaluating the efficacy and safety of acotiamide in patients with esophagogastric junction outflow obstruction: study protocol for an investigator-initiated, multi-center,randomized, double-blind, placebo-controlled phase II trial.
Trials 24(1): 459, 2023

Kawasaki A, Tsuji K, Uedo N, Kanesaka T, Miyamoto H, Gushima R, Minoda Y, Ihara E, Amano R, Yao K, Naito Y, Aoyagi H, Iwasaki T, Uchita K, Arima H, Doyama H: Non-atrophic gastric mucosa is an independent associated factor for superficial non-ampullary duodenal epithelial tumors: a multicenter, matched, case-control study. 
Clin Endosc 56(1): 75-82, 2023

Minoda Y, Esaki M, Ihara E, Nagatomo S, Nishioka K, Fujimori N, Ogino H, Bai X, Tanaka Y, Chinen T, Hu Q, Ota M, Umekita S, Yamamoto H, Ogawa Y: Auxilliary diagnosis of subepithelial lesions by impedance measurement during endoscopic ultrasound fine-needle aspiration biopsy.
Gastrointest Endosc 97(5): 977-984, 2023

Minoda Y, Ihara E, Itaba S, Sumida Y, Haraguchi K, Aso A, Mizutani T, Osoegawa T, Esaki M, Nagatomo S, Nishioka K, Muta K, Bai X, Ogino H, Fujimori N, Tsurumaru D, Ohuchida K, Qingjiang H, Oki E, Yamamoto H, Ogawa Y: Negligible procedure-related dissemination risk of mucosal incision-assisted biopsy for gastrointestinal stromal tumors versus endoscopic ultrasound-guided fine-needle aspiration/biopsy.
Surg Endosc 37(1): 101-108, 2023

Hata Y, Sato H, Shimaura Y, Abe H, Shiwaku A, Shiota J, Sato C, Ominami M, Fukuda H, Ogawa R, Nakamura J, Tatsuta T, Ikebuchi Y, Yokomichi H, Ihara E, Inoue H: Impact of peroral endoscopic myotomy on high-resolution manometry findings and their association with the procedure’s outcomes. 
Gastrointest Endosc 97(4): 673-683.e2, 2023

Igarashi HY, Ihara E, Bai X, Higashi C, Ikeda H, Tanaka Y, Hirano M, Ogino H, Chinen T, Taguchi Y, Ogawa Y: Determination of region-specific roles of the M3 muscarinic acetylcholine receptor in gastrointestinal motility. 
Dig Dis Sci 68(2): 439-450,2023

Esaki M, Ihara E, Sumida Y, Fujii H, Takahashi S, Haraguchi K, Iwasa T, Somada S, Minoda Y, Ogino H, Tagawa K, Ogawa Y: Hybrid- and conventional endoscopic submucosal dissection for early gastric neoplasm: a multi-center randomized controlled trial. 
Clin Gastroenterol Hepatol 21(7):1810-1818.e8, 2023

Ogino H, Morikubo H, Fukaura K, Okui T, Gardiner S, Sugiyama N, Yoshii N, Kawaguchi T, Chen H, Nonnenmacher E, Setoguchi S, Nakashima N, Kobayashi T: Validation of a claims-based algorithm to identify cases of ulcerative colitis in Japan. J Gastroenterol Hepatol37(3):499-506, 2022

Yamakawa M, Nakane S, Ihara E, Tawara N, Ikeda H, Igarashi Y, Komohara Y, Takamatsu K, Ikeda T, Tomita Y, Murai S, Ando Y, Mukaino A, Ogawa Y, Ueda M: A novel murine model of autoimmune dysautonomia by alpha3 nicotinic acetylcholine receptor immunization. Front Neurosci 161006923, 2022

Sasaki T, Kohashi K, Kawatoko S, Ihara E, Oki E, Nakamura M, Ogawa Y, Oda Y: Tumor progression by epithelial-mesenchymal transition in arid1a- and smarca4-aberrant solid-type poorly differentiated gastric adenocarcinoma. Virchows Arch 480(5): 1063-1075, 2022

Ohkubo A, Osoegawa T, Harada N, Iboshi Y, Sumida Y, Nakamuta M, Suematsu E, Kobayashi H, Ihara E: A rare case of rheumatoid arthritis with tocilizumab-induced intestinal mucosal injury. Intern Med 61(7): 1011-1014, 2022

Minoda Y, Ogino H, Sumida Y, Osoegawa T, Itaba S, Hashimoto N, Esaki M, Kitagawa Y, Yodoe K, Iboshi Y, Matsuguchi T, Tadokoro M, Chaen T, Kubo H, Kubokawa M, Harada N, Nishizima K, Fujii H, Hata Y, Tanaka Y, Ihara E, Ogawa Y: Is a small-caliber or large-caliber endoscope more suitable for colonic self-expandable metallic stent placement? A randomized controlled study. Therap Adv Gastroenterol 1517562848211065331, 2022

Minoda Y, Ihara E, Itaba S, Sumida Y, Haraguchi K, Aso A, Mizutani T, Osoegawa T, Esaki M, Nagatomo S, Nishioka K, Muta K, Bai X, Ogino H, Fujimori N, Tsurumaru D, Ohuchida K, Qingjiang H, Oki E, Yamamoto H, Ogawa Y: Negligible procedure-related dissemination risk of mucosal incision-assisted biopsy for gastrointestinal stromal tumors versus endoscopic ultrasound-guided fine-needle aspiration/biopsy. Surg Endosc 2022

Minoda Y, Ihara E, Fujimori N, Nagatomo S, Esaki M, Hata Y, Bai X, Tanaka Y, Ogino H, Chinen T, Hu Q, Oki E, Yamamoto H, Ogawa Y: Efficacy of ultrasound endoscopy with artificial intelligence for the differential diagnosis of non-gastric gastrointestinal stromal tumors. Sci Rep 12(1): 16640, 2022

Minoda Y, Esaki M, Ihara E, Nagatomo S, Nishioka K, Fujimori N, Ogino H, Bai X, Tanaka Y, Chinen T, Hu Q, Ota M, Umekita S, Yamamoto H, Ogawa Y: Auxiliary diagnosis of subepithelial lesions by impedance measurement during endoscopic ultrasound guided fine-needle biopsy. Gastrointest Endosc 2022

Matsumoto K, Fujimori N, Hata Y, Minoda Y, Murakami M, Teramatsu K, Takamatsu Y, Takeno A, Oono T, Ihara E, Nakata K, Nakamura M, Yamamoto T, Koga Y, Oda Y, Ito T, Ogawa Y: Ampullary neuroendocrine neoplasm: Clinicopathological characteristics and novel endoscopic entity. Dig Dis 2022

Iwakiri K, Fujiwara Y, Manabe N, Ihara E, Kuribayashi S, Akiyama J, Kondo T, Yamashita H, Ishimura N, Kitasako Y, Iijima K, Koike T, Omura N, Nomura T, Kawamura O, Ohara S, Ozawa S, Kinoshita Y, Mochida S, Enomoto N, Shimosegawa T, Koike K: Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021. J Gastroenterol 57(4): 267-285, 2022

Ihara E, Ogino H, Muta K, Hamada S, Wada M, Hata Y, Ikeda H, Bai X, Minoda Y, Esaki M, Tanaka Y, Chinen T, Ogawa Y: The treatment effects of acotiamide in esophagogastric outflow obstruction: A prospective longitudinal observational study. Esophagus 19(2): 332-342, 2022

Iboshi Y, Sumida Y, Ihara E, Fujii H, Harada N, Nakamuta M, Ogawa Y: Over-the-catheter endoscope replacement for stenting in patients with inaccessible malignant colonic obstruction with coexisting peritoneal carcinomatosis. Dig Endosc 2022

Hata Y, Ihara E, Wada M, Tsuru H, Muta K, Minoda Y, Bai X, Esaki M, Tanaka Y, Chinen T, Ogino H, Sakamoto R, Ogawa Y: Improved esophagography screening for esophageal motility disorders using wave appearance and supra-junctional ballooning. J Gastroenterol 57(11): 838-847, 2022

Hamada S, Ihara E, Yoshitake C, Inada T, Fukuya H, Ohkubo A, Tomoeda N, Iboshi Y, Sumida Y, Yoshimura D, Nakamuta M, Harada N: Clip stopper closure method using a detachable snare in combination with zeoclip for endoscopic submucosal dissection-induced mucosal defects. Dig Endosc 2022

Hamada S, Ihara E, Muta K, Wada M, Hata Y, Ikeda H, Tanaka Y, Ogino H, Chinen T, Ogawa Y: Onigiri esophagography as a screening test for esophageal motility disorders. J Neurogastroenterol Motil 28(1): 43-52, 2022

Fukuda S, Ichida K, Kitagawa Y, Nakano K, Chaen T, Yoshimura D, Ochiai T, Ihara E, Ogawa Y: An adult case of congenital duodenal diaphragm that was successfully treated by endoscopic resection using a grasping-type scissor forceps. DEN Open 2e93, 2022

Esaki M, Yamakawa S, Ichijima R, Suzuki S, Kusano C, Ikehara H, Minoda Y, Ihara E, Gotoda T: Self-completion method of endoscopic submucosal dissection using the endosaber for treating colorectal neoplasms (with video). Sci Rep 12(1): 5821, 2022

Esaki M, Minoda Y, Ihara E: In living color: Linked color imaging for the detection of early gastric cancer. Dig Dis Sci 67(6): 1922-1924, 2022

Esaki M, Maehara R, Nagatomo S, Nishioka K, Minoda Y, Ogino H, Ihara E: Application of traction-method to hybrid endoscopic submucosal dissection for gastrointestinal tumors. Endoscopy 54(4): E160-E161, 2022

Esaki M, Ihara E, Sumida Y, Fujii H, Takahashi S, Haraguchi K, Iwasa T, Somada S, Minoda Y, Ogino H, Tagawa K, Ogawa Y: Hybrid- and conventional endoscopic submucosal dissection for early gastric neoplasms: A multi-center randomized controlled trial. Clin Gastroenterol Hepatol 2022

Esaki M, Ihara E, Fujii H, Sumida Y, Haraguchi K, Takahashi S, Iwasa T, Nakano K, Wada M, Somada S, Minoda Y, Ogino H, Tagawa K, Ogawa Y: Comparison of the procedure time differences between hybrid endoscopic submucosal dissection and conventional endoscopic submucosal dissection in patients with early gastric neoplasms: A study protocol for a multi-center randomized controlled trial (hybrid-g trial). Trials 23(1): 166, 2022

Esaki M, Ihara E, Esaki M, Nishioka K, Kimura Y, Hata Y, Tsuru H, Wada M, Minoda Y, Bai X, Shoguchi Y, Nasu T, Nagatomo S, Muta K, Ogino H, Ogawa Y: Comparisons of outcomes between proknife injection endoscopic submucosal dissection and conventional endoscopic submucosal dissection for large gastric lesions in ex vivo porcine model study: A randomized controlled trial. DEN open 2(1): e91, 2022

Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y: Involvement of interstitial cells of cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. Eur J Pharmacol 910174491, 2021

Okuno H, Ogino H, Ihara E, Nishioka K, Tanaka Y, Chinen T, Kohjima M, Oono T, Tanaka M, Goya T, Fujimori N, Iboshi Y, Gotoda T, Ogawa Y: Discriminant equation using mucosally expressed cytokines and transcription factor for making definite diagnosis of inflammatory bowel disease unclassified. BMC Gastroenterol 21(1): 73, 2021

Okuno H, Ogino H, Ihara E, Nishioka K, Iboshi Y, Chinen T, Ochiai T, Akiho H, Nakamura K, Gotoda T, Ogawa Y: Interleukin-1beta as a predictor of glucocorticoid response in ulcerative colitis. Digestion 102(3): 357-367, 2021

Ogino H, Fukaura K, Iboshi Y, Nagamatsu Y, Okuno H, Nishioka K, Nishihara Y, Tanaka Y, Chinen T, Ihara E, Ogawa Y: Role of the il-23-t-bet/gata3 axis for the pathogenesis of ulcerative colitis. Inflammation 44(2): 592-603, 2021

Nishioka K, Ogino H, Chinen T, Ihara E, Tanaka Y, Nakamura K, Ogawa Y: Mucosal il23a expression predicts the response to ustekinumab in inflammatory bowel disease. J Gastroenterol 56(11): 976-987, 2021

Nishihara Y, Ogino H, Tanaka M, Ihara E, Fukaura K, Nishioka K, Chinen T, Tanaka Y, Nakayama J, Kang D, Ogawa Y: Mucosa-associated gut microbiota reflects clinical course of ulcerative colitis. Sci Rep 11(1): 13743, 2021

Nasu T, Esaki M, Shoguchi Y, Bai X, Minoda Y, Ogino H, Ihara E: Traction-assisted hybrid endoscopic submucosal dissection for small rectal neuroendocrine tumors. Endoscopy 2021

Nakane S, Mukaino A, Ihara E, Ogawa Y: Autoimmune gastrointestinal dysmotility: The interface between clinical immunology and neurogastroenterology. Immunol Med 44(2): 74-85, 2021

Nagatomo S, Minoda Y, Ihara E: Double scope recovery technique to manage procedure-related trouble during wire trimming with a loop cutter. Dig Endosc 33(4): e83-e84, 2021

Muta K, Ihara E, Hamada S, Ikeda H, Wada M, Hata Y, Bai X, Nishihara Y, Tanaka Y, Ogino H, Ogawa Y: Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows. Sci Rep 11(1): 7898, 2021

Minoda Y, Hisamatsu Y, Ihara E: Usefulness of preoperative site marking with an indocyanine green fluorescent clip for gastrointestinal stromal tumor. Dig Endosc 33(5): e95-e96, 2021

Hamada S, Ihara E, Ikeda H, Muta K, Ogino H, Chinen T, Tanaka Y, Ogawa Y: Clinical characterization of vonoprazan-refractory gastroesophageal reflux disease. Digestion 102(2): 197-204, 2021

Fujimori N, Osoegawa T, Aso A, Itaba S, Minoda Y, Murakami M, Matsumoto K, Teramatsu K, Takamatsu Y, Takaoka T, Oono T, Ihara E, Yoshizumi T, Ohtsuka T, Nakamura M, Ogawa Y: Efficacy of early endoscopic ultrasound-guided transluminal drainage for postoperative pancreatic fistula. Can J Gastroenterol Hepatol 20216691705, 2021

Esaki M, Minoda Y, Wada M, Sakisaka S, Tsuruta S, Hosokawa T, Matsuguchi T, Ichijima R, Suzuki S, Tamura Y, Iwao A, Yamakawa S, Irie A, Ihara E, Ogawa Y: Self-completion method of endoscopic submucosal dissection using endosaber without any other device or assistance: An ex vivo porcine model study. Digestion 102(2): 139-146, 2021

Esaki M, Ihara E, Hashimoto N, Abe S, Aratono C, Shiga N, Sumida Y, Fujii H, Haraguchi K, Takahashi S, Iwasa T, Nakano K, Wada M, Somada S, Nishioka K, Minoda Y, Ogino H, Ogawa Y: Efficacy of hybrid endoscopic submucosal dissection with souten in gastric lesions: An ex vivo porcine model basic study. World J Gastrointest Surg 13(6): 563-573, 2021

Esaki M, Ihara E, Gotoda T: Endoscopic instruments and techniques in endoscopic submucosal dissection for early gastric cancer. Expert Rev Gastroenterol Hepatol 15(9): 1009-1020, 2021

Esaki M, Horii T, Ichijima R, Wada M, Sakisaka S, Abe S, Tomoeda N, Kitagawa Y, Nishioka K, Minoda Y, Tsuruta S, Suzuki S, Akiho H, Ihara E, Ogawa Y, Gotoda T: Assistant skill in gastric endoscopic submucosal dissection using a clutch cutter. World J Gastrointest Surg 13(2): 116-126, 2021

Esaki M, Esaki M, Maehara K, Minoda Y, Ogino H, Ihara E, Ogawa Y: Rubber band-assisted, one-person-operated cold snare polypectomy for colorectal polyps. Endosc Int Open 9(11): E1845-E1846, 2021

Tsuruta S, Kohashi K, Yamada Y, Fujiwara M, Koga Y, Ihara E, Ogawa Y, Oki E, Nakamura M, Oda Y: Solid-type poorly differentiated adenocarcinoma of the stomach: Deficiency of mismatch repair and swi/snf complex. Cancer Sci 111(3): 1008-1019, 2020

Oyama K, Ohuchida K, Shindo K, Moriyama T, Hata Y, Wada M, Ihara E, Nagai S, Ohtsuka T, Nakamura M: Thoracoscopic surgery combined with endoscopic creation of a submucosal tunnel for a large complicated esophageal leiomyoma. Surg Case Rep 6(1): 92, 2020

Minoda Y, Ihara E, Ogino H, Komori K, Otsuka Y, Ikeda H, Esaki M, Chinen T, Matsuguchi T, Takahashi S, Shiga N, Yoshimura R, Ogawa Y: The efficacy and safety of a promising single-channel endoscopic closure technique for endoscopic treatment-related artificial ulcers: A pilot study. Gastrointest Tumors 7(1-2): 21-29, 2020

Minoda Y, Ihara E, Komori K, Ogino H, Otsuka Y, Chinen T, Tsuda Y, Ando K, Yamamoto H, Ogawa Y: Efficacy of endoscopic ultrasound with artificial intelligence for the diagnosis of gastrointestinal stromal tumors. J Gastroenterol 55(12): 1119-1126, 2020

Minoda Y, Chinen T, Osoegawa T, Itaba S, Haraguchi K, Akiho H, Aso A, Sumida Y, Komori K, Ogino H, Ihara E, Ogawa Y: Superiority of mucosal incision-assisted biopsy over ultrasound-guided fine needle aspiration biopsy in diagnosing small gastric subepithelial lesions: A propensity score matching analysis. BMC Gastroenterol 20(1): 19, 2020

Harada N, Hirowatari M, Ihara E, Ishihara E, Inoue M, Miyamura T, Nakamuta M: A case of suspicious allergic reaction to peracetic acid following endoscopy. Clin Endosc 53(6): 743-745, 2020

Fujimori N, Minoda Y, Murakami M, Suehiro Y, Oono T, Ihara E, Ogawa Y: Endoscopic removal of a lumen-apposing metal stent that migrated into the walled-off necrosis during the first drainage procedure. Endoscopy 52(2): E51-E52, 2020

Esaki M, Minoda Y, Ihara E, Sakisaka S, Tsuruta S, Hosokawa T, Wada M, Hata Y, Suzuki S, Iwao A, Yamakawa S, Irie A, Akiho H, Ogawa Y: Efficacy of traction, using a clip-with-thread, for esophageal endoscopic submucosal dissection for esophageal lesions with fibrosis in an ex vivo pig training model. Turk J Gastroenterol 31(1): 58-64, 2020

Esaki M, Hayashi Y, Ikehara H, Ihara E, Horii T, Tamura Y, Ichijima R, Yamakawa S, Irie A, Shibuya H, Suzuki S, Kusano C, Minoda Y, Akiho H, Ogawa Y, Gotoda T: The effect of scissor-type versus non-scissor-type knives on the technical outcomes in endoscopic submucosal dissection for superficial esophageal cancer: A multi-center retrospective study. Dis Esophagus 33(4): 2020

Esaki M, Haraguchi K, Akahoshi K, Tomoeda N, Aso A, Itaba S, Ogino H, Kitagawa Y, Fujii H, Nakamura K, Kubokawa M, Harada N, Minoda Y, Suzuki S, Ihara E, Ogawa Y: Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors. World J Gastrointest Oncol 12(8): 918-930, 2020

Tsuruta S, Ohishi Y, Fujiwara M, Ihara E, Ogawa Y, Oki E, Nakamura M, Oda Y: Gastric hepatoid adenocarcinomas are a genetically heterogenous group; most tumors show chromosomal instability, but msi tumors do exist. Hum Pathol 8827-38, 2019

Osoegawa T, Minoda Y, Ihara E, Komori K, Aso A, Goto A, Itaba S, Ogino H, Nakamura K, Harada N, Makihara K, Tsuruta S, Yamamoto H, Ogawa Y: Mucosal incision-assisted biopsy versus endoscopic ultrasound-guided fine-needle aspiration with a rapid on-site evaluation for gastric subepithelial lesions: A randomized cross-over study. Dig Endosc 31(4): 413-421, 2019

Minoda Y, Ogino H, Chinen T, Ihara E, Haraguchi K, Akiho H, Takizawa N, Aso A, Tomita Y, Esaki M, Komori K, Otsuka Y, Iwasa T, Ogawa Y: Objective validity of the japan narrow-band imaging expert team classification system for the differential diagnosis of colorectal polyps. Dig Endosc 31(5): 544-551, 2019

Minoda Y, Fujimori N, Ihara E: Forward-viewing endoscopic ultrasound-guided fine-needle biopsy using the clip-with-thread method for small gastric subepithelial lesions. Dig Endosc 31(6): e103-e104, 2019

Komori K, Ihara E, Minoda Y, Ogino H, Sasaki T, Fujiwara M, Oda Y, Ogawa Y: The altered mucosal barrier function in the duodenum plays a role in the pathogenesis of functional dyspepsia. Dig Dis Sci 64(11): 3228-3239, 2019

Fukaura K, Iboshi Y, Ogino H, Ihara E, Nakamura K, Nishihara Y, Nishioka K, Chinen T, Iwasa T, Aso A, Goto A, Haraguchi K, Akiho H, Harada N, Ogawa Y: Mucosal profiles of immune molecules related to t helper and regulatory t cells predict future relapse in patients with quiescent ulcerative colitis. Inflamm Bowel Dis 25(6): 1019-1027, 2019

Bai X, Ihara E, Otsuka Y, Tsuruta S, Hirano K, Tanaka Y, Ogino H, Hirano M, Chinen T, Akiho H, Nakamura K, Oda Y, Ogawa Y: Involvement of different receptor subtypes in prostaglandin e2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body. Eur J Pharmacol 857172405, 2019

H. Hayashi, M. Esaki, S. Suzuki, T. Hosokawa, Y. Tanaka, T. Mizutani, S. Tsuruta, A. Iwao, S. Yamakawa, A. Irie, Y. Minoda, Y. Hata, H. Ogino, H. Akiho, E. Ihara, Y. Ogawa. The efficacy of scissor-type knife in endoscopic submucosal dissection for early gastric neoplasms: a propensity score matching analysis. World Journal of Gastrointestinal Oncology. 10:487-495,2018

Campbell C, Dikiy S, Bhattarai SK, Chinen T, Matheis F, Calafiore M, Hoyos B, Hanash A, Mucida D, Bucci V, Rudensky AY. Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance. Immunity. 48:1245-1257,2018

M. Esaki, S. Suzuki, Y. Hayashi, A. Yokoyama, S. Abe, T. Hosokawa, S. Tsuruta, Y. Minoda, Y. Hata, H. Ogino, H. Akiho, E. Ihara and Y. Ogawa. Propensity score-matching analysis to compare clinical outcomes of endoscopic submucosal dissection for early gastric cancer in the postoperative and non-operative stomachs. BMC Gastroenterol 18:125, 2018

M. Mukaino, H. Minami, H. Isomoto, H. Hamamoto, E. Ihara. Y. Maeda, O. Higuchi, T. Okanishi, Y. Kokudo, K. Deguchi, F. Sasaki, T. Ueki, K. Murata, T. Yoshida, M. Kinjo, Y. Ogawa, A. Ido, H. Matsuo, K. Nakao, S. Nakane. Anti-ganglionic acetylcholine receptor antibodies in Japanese patients with motility disorders. J Gastroenterol 53:1227-1240, 2018

T. Iwasa, R. Nakadate, S. Onogi, Y. Okamoto, J. Arata, S. Oguri, H. Ogino H, E. Ihara, K. Ohuchida, T. Akahoshi, T. Ikeda, Y. Ogawa, M. Hashizume. A new robotic-assisted flexible endoscope with single-hand control: endoscopic submucosal dissection in the ex vivo porcine stomach. Surgical Endoscopy 32:3386-3392, 2018

K. Fukaura, E. Ihara, H. Ogino, Y. Iboshi, K. Muta, X. Bai, S. Hamada, Y. Hata, T. Iwasa, A. Aso, K. Nakamura, Y. Ogawa. Mucosally expressed cytokines are associated with the esophageal motility function. Digestion 98:95-103, 2018

M. Esaki, S. Suzuki, Y. Hayashi, A. Yokoyama, S. Abe, T. Hosokawa, H. Ogino, H. Akiho, E. Ihara, Y. Ogawa. Splash M-knife versus Flush Knife BT in the technical outcomes of endoscopic submucosal dissection for early gastric cancer: a propensity score matching analysis. BMC Gastroenterol 18:35, 2018

K. Nakano, H. Yamamoto, M. Fujiwara, Y. Koga, S. Tsuruta, E. Ihara, E. Oki, M. Nakamura, Y. Ogawa, Y. Oda. Clinicopathogenic and molecular characteristics of synchronous colorectal carcinoma with mismatch repair deficiency. Am J Surg Pathol 42:172-182, 2018

Bai X, Ihara E, Hirano K, Tanaka Y, Nakano K, Kita S, Iwamoto T, Ogino H, Hirano M, Nakamura K, Ogawa Y. Endogenous hydrogen sulfide contributes to tone generation in porcine lower esophageal sphincter via Na+/Ca2+ exchanger. Cell Mol Gastroenterol Hepatol 5;209-221, 2017

Otsuka Y, Akahoshi K, Yasunaga K, Kubokawa M, Gibo J, Osada S, Tokumaru K, Miyamoto K, Sato T, Shiratsuchi Y, Oya M, Koga H, Ihara E and Nakamura K. Clinical outcome of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer. World J Gastrointest Oncol 9:416-422, 2017

Motomura Y, Akahoshi K, Kajiyama K, Gibo J, Miyamoto K, Ikeda H, Yamaguchi E, Teramatsu K, Utsunomiya R, Miyagaki A, Ooya M and Ihara E. Utility of lavage cytology plus targeted biopsy during cholangioscopy for the diagnosis of indeterminate biliary lesions. Gastroenterol Hepatol Endosc 2:1-4, 2017

Akahoshi K, Kubokawa M, Gibo J, Osada S, Tokumaru K, Yamaguchi E, Ikeda H, Sato T, Miyamoto K, Kimura Y, Shiratsuchi Y, Oya M, Koga H, Ihara E, Nakamura K. Endoscopic submucosal dissection of gastric adenoma using the clutch cutter. World J Gastrointest Endosc. 9:334-340, 2017

Komori K, Kubokawa M, Ihara E, Akahoshi K, Nakamura K, Motomura K, Masumoto A. Prognostic factors associated with mortality in patients with gastric fundal varieal bleeding World J Gastroenterol. 23:496-504, 2017

Bai X, Tanaka Y, Ihara E, Hirano K, Nakano K, Hirano M, Oda Y and Nakamura K. Trypsin induces biphasic muscle contraction and relaxation via transient receptor vanilloid 1 and neurokinin receptor 1/2 in porcine esophageal body. Eur J Pharmacol. 797:65-74, 2017

Akahoshi K, Kubokawa M, Gibo J, Osada S, Tokumaru K, Shiratsuchi Y, Oya M, Ihara E, Nakamura K.  Endoscopic resection using the Clutch Cutter and a detachable snare for large pedunculated colonic polyps. Endoscopy 49:54-58, 2017

Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY.An essential role for the IL-2 receptor in Treg cell function.Nat Immunol.  17:1322-1333, 2016

Tanaka Y, Ihara E, Nakamura K, Muta K, Fukaura K, Mukai K, Xiaopeng B, Takayanagi R: Clinical characteristics associated with esophageal motility function. J Gastroenterol Hepatol 31:1133-1140, 2016

Nakamura K, Ihara E, Akiho H, Akahoshi K, Harada N, Ochiai T, Nakamura N, Ogino H, Iwasa T, Aso A, Iboshi Y, Takayanagi R: Limited effects of rebamipide in addition to proton pump inhibitor (PPI) in the treatment of post-endoscopic submucosal dissection gastric ulcers: a randomized controlled trial comparing PPI plus rebamipide combination therapy with PPI monotherapy. Gut and Liver 10:917-924, 2016

Muta K, Ihara E, Fukaura K, Tsuchida O, Ochiai T, Nakamura K: Effects of acotiamide on esophageal motility function in patients with esophageal motility disorders: a pilot study. Digestion 94:9-16, 2016

Komori K, Nakamura K, Ihara E, Iwasa T, Hirahashi M, Oda Y, Takayanagi R: Endoscopic submucosal dissection is feasible for very elderly patients with early gastric cancer: comparison of short-term and long-term outcomes in very elderly and non-elderly patients. Fukuoka Acta Medica 107:72-81, 2016

Aso A, Yoshinaga S: Future potential means of diagnosing gastric subepithelial lesions: Beyond conventional endoscopic ultrasound and endoscopic ultrasound-guided fine-needle aspiration. Dig Endosc Suppl1:32-33, 2016

Nakamura K, Osada M, Goto A, Iwasa T, Takahashi S, Takizawa N, Akahoshi K, Ochiai T, Nakamura N, Akiho H, Itaba S, Harada N, Iji M, Tanaka M, Kubo H, Somada S, Ihara E, Oda Y, Ito T, Takayanagi R: Short- and long-term outcomes of endoscopic resection of rectal neuroendocrine tumors: analyses according to the WHO 2010 classification. Scand J Gastroenterol 51:448-455, 2016

Tanaka Y, Ihara E, Hirano K, Takahashi S, Hirano M, Nakamura K, Akiho H, Oda Y, Takayanagi R: Trypsin-induced biphasic regulation of tone in the porcine lower esophageal sphincter. Eur J Phamacol 752:97-105, 2015

Ihara E, Yu Q, Chappellaz M, MacDonald JA: ERK and p38MAPK pathways regulate myosin light chain phosphatase and contribute to Ca2+ sensitization of intestinal smooth muscle contraction. Neurogastroenterol Motil 27:135-146, 2015

Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY.Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.Cell. 158:749-63, 2014

Osada M, Aishima S, Hirahashi M, Takizawa N, Takahashi S, Nakamura K, Tanaka M, Maehara Y, Takayanagi R, Oda Y: Combination of hepatocellular markers is useful for prognostication in gastric hepatoid adenocarcinoma. Human Pathology 45:1243-1250, 2014

Iboshi Y, Nakamura K, Ihara E, Iwasa T, Akiho H, Harada N, Nakamuta M, Takayanagi R: Multigene analysis unveils distinctive expression profiles of helper T cell-related genes in the intestinal mucosa that discriminate between ulcerative colitis and Crohn' disease. Inflammatory Bowel Diseases 20:967-977, 2014

Akiho H, Tokita Y, Nakamura K, Satoh K, Nishiyama M, Tsuchiya N, Tsuchiya K, Ohbuchi K, Iwakura Y, Ihara E, Takayanagi R, Yamamoto M: Involvement of interleukin-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut motor dysfunction. PLOS ONE 9:e92960, 2014

Aso A, Ihara E, Osoegawa T, Nakamura K, Itaba S, Igarashi H, Ito T, Aishima S, Oda Y, Tanaka M, Takayanagi R: Key endoscopic ultrasound features of pancreatic ductal adenocarcinoma smaller than 20 mm. Scand J Gastroenterol 49:332-338, 2014

Ihara E, Matsuzaka H, Honda K, Hata Y, Sumida Y, Akiho H, Misawa T, Toyoshima S, Chijiiwa Y, Nakamura K, Takayanagi R: Mucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors. World J Gastrointest Endosc 5:191-196, 2013

Akahoshi K, Minoda Y, Komori K, Motomura Y, Kubokawa M, Otsuka Y, Hamada S, Fukuda S, Iwao R, Gibo J, Oya M, Nakamura K: Endoscopic submucosal dissection using the "Clutch Cutter" for early esophageal squamous cell carcinoma. Endoscopy 45:1035-1038, 2013

Itaba S, Nakamura K, Aso A, Tokunaga S, Akiho H, Ihara E, Iboshi Y, Iwasa T, Akahoshi K, Ito T, Takayanagi R: Prospective, randomized, double-blind, placebo-controlled trial of ulinastatin for prevention of hyperenzymemia after double balloon endoscopy via the antegrade approach. Dig Endosc 25:421-427, 2013

Higuchi N, Nakamura K, Ihara E, Akahoshi K, Akiho H, Sumida Y, Motomura Y, Kubokawa M, Ito T, Takayanagi R: Preserved gastric motility in patients with early gastric cancer after endoscopic submucosal dissection. J Gastroenterol Hepatol 28:494-498, 2013

Josefowicz S, Niec R, Kim HY, Treuting P, Chinen T, Umetsu DT, Rudensky AY. Extrathymically generated regulatory T cells control mucosal Th2 inflammation. Nature.  482:395-9, 2012

Ihara E, Chappellaz M, Turner SR, MacDonald JA: The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis. Neurogastroenterol Motil 24:e15-26, 2012

Iwasa T, Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R: Feeding administration of Daikenchuto suppresses colitis induced by naive CD4+ T cell transfer into SCID mice. Dig Dis Sci 57:2571-2579, 2012

Somada S, Muta H, Nakamura K, Sun X, Honda K, Ihara E, Akiho H, Takayanagi R, Yoshikai Y, Podack ER, Tani K: CD30 ligand/CD30 interaction is involved in pathogenesis of inflammatory bowel disease. Dig Dis Sci 57: 2031-2037, 2012

Ogino H, Nakamura K, Iwasa T, Ihara E, Akiho H, Motomura Y, Akahoshi K, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R: Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. J Gastroenterol 47: 366-376, 2012

Ihara E, Chappellaz M, Turner SR, MacDonald JA: The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis. Neurogastroenterol Motil 24:e15-26, 2012

Chinen T, Komai K, Muto G, Morita R, Inoue N, Yoshida H, Sekiya T, Nakamura K, Yoshimura A. Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance. Nat Commun. 2:190, 2011

Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Chinen T, Yoshimura A. SOCS1 is essential for Treg cell functions by preventing loss of Foxp3 expression as well as IFN-g and IL-17A production. J Exp Med. 208:2055-67, 2011

Itaba S, Iboshi Y, Nakamura K, Ogino H, Sumida Y, Aso A, Yoshinaga S, Akiho H, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R: Low-frequency of bacteremia after endoscopic submucosal dissection of the stomach. Dig Endosc 23: 69-72, 2011

Goto A, Hirahashi M, Osada M, Nakamura K, Yao T, Tsuneyoshi M, Takayanagi R, Oda Y:
Aberrant activation-induced cytidine deaminase expression is associated with mucosal intestinalization in the early stage of gastric cancer. Virchows Arch 458: 717-724, 2011

Kanayama K, Nakamura K, Ogino H, Sumida Y, Ihara E, Akiho H, Takayanagi R: Th1 responses are more susceptible to infliximab-mediated immunosuppression than Th17 responses. Dig Dis Sci 56: 3525-3533, 2011

Ogino H, Nakamura K, Iwasa T, Ihara E, Akiho H, Motomura Y, Akahoshi K, Igarashi H, Kato M, Kotoh K, Ito T, Takayanagi R: Regulatory T Cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. J Gastroenterol 47: 366-376, 2012

Akiho H, Nakamura K: Daikenchuto ameliorated muscle hypercontractility in a murine T-cell-mediated persistent gut motor dysfunction model. Digestion 83: 173-179, 2011

Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R: CD4+CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model. Dig Dis Sci 56: 376-386, 2011

Iwasa T, Nakamura K, Ogino H, Itaba S, Akiho H, Okamoto R, Iboshi Y, Aso A, Murao H, Kanayama K, Ito T, Takayanagi R: Multiple ulcers in the small and large intestines occurred during tocilizumab therapy for rheumatoid arthritis. Endoscopy 43: 70-72, 2011

Akiho K, Honda K, Motomura Y, Kubokawa M, Okamoto R, Osoegawa T, Nakama N, Kashiwabara Y, Higuchi N, Tanaka Y, Oya M, Nakamura K: Endoscopic submucosal dissection using a grasping-type scissors forceps for early gastric cancers and adenomas. Dig Endosc 23: 24-29, 2011

Chinen T, Volchkov PY, Chervonsky AV, Rudensky AY. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. J Exp Med.  207:2323-30, 2010

Mizutani T, Akiho H, Khan WI, Murao H, Ogino H, Kanayama K, Nakamura K, Takayanagi R: Persistent gut motor dysfunction in a murine model of T-cell-induced enteropathy. Neurogastroenterol Motil 22: 196-203, 2010

Yoshinaga M, Kitamura Y, Chaen T, Yamashita S, Tsuruta S, Hisano T, Ikeda Y, Sakai H, Nakamura K, Takayanagi R, Muto Y: The simultaneous expression of peroxisome proliferator-activated receptor delta and cyclooxygenase-2 may enhance angiogenesis and tumor venous invasion in tissues of colorectal cancers. Dig Dis Sci 54: 1108-1114, 2009

Harada N, Sumida Y, Nakamura K, Itaba S, Yoshinaga S, Mizutani T, Honda K, Taki K, Murao H, Ogino H, Kanayama K, Akiho H, Goto A, Segawa Y, Yao T, Takayanagi R: Impact of double-balloon endoscopy on the diagnosis of jejunoileal involvement in primary intestinal follicular lymphomas: a case series. Endoscopy 41: 175-178, 2009

Kubo H, Nakamura K, Itaba S, Yoshinaga S, Kinukawa N, Sadamoto Y, Ito T, Yonemasu H, Takayanagi R: Differential diagnosis of cystic tumors of the pancreas by endoscopic ultrasonography. Endoscopy 41: 684-689, 2009

Ihara E, Moffat L, Borman MA, Amon JE, Walsh MP, MacDonald JA: Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide. Am J Physiol Gastrointest Liver Physiol 297: G361-370, 2009

Ichiyama K, Yoshida H, Wakabayashi Y, Chinen T, Saeki K, Takaesu G, Hori S, Yoshimura A, Kobayashi T. Foxp3 inhibits RORgt-mediated IL-17A mRNA transcription through direct interaction with RORgt. J Biol Chem. 283:17003-8, 2008

Sumida Y, Nakamura K, Kanayama K, Akiho H, Teshima T, Takayanagi R: Preparation of functionally preserved CD4+CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell-transfer therapy. Cytotherapy 10: 698-710, 2008

Motomura Y, Ghia J-E, Wang H, Akiho H, El-Sharkawy RT, Collins M, Wan Y, McLaughlin JT, Khan WI: Enterochromaffin cell and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments. Gut 57:475-481, 2008

Sun X, Somada S, Shibata K, Muta H, Yamada H, Yoshihara H, Honda K, Nakamura K, Takayanagi R, Tani K, Podack ER, Yoshikai Y: A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology 134: 447-58, 2008

Yoshinaga S, Gotoda T, Kusano C, Oda I, Nakamura K, Takayanagi R: Clinical impact of endoscopic submucosal dissection for superficial adenocarcinoma located at the esophagogastric junction. Gastrointest Endosc 67: 202-9, 2008