研究室紹介
Our Laboratories
研究室紹介
Our Laboratories
血液研究室
受賞
・第14回 臨床医学研究塾（2023年10月 大阪大学） Clinical Investigator Award
・第60回日本臨床分子医学会学術集会（2025年4月 リーガロイヤルホテル大阪） 学術奨励賞（YIA）
・第50回日本骨髄腫学会学術集会（2025年5月 Gメッセ群馬） 優秀演題賞
・2025年度 公益信託 日本白血病研究基金 一般研究賞
・第60回日本臨床分子医学会学術集会（2025年4月 リーガロイヤルホテル大阪） 学術奨励賞（YIA）
・第50回日本骨髄腫学会学術集会（2025年5月 Gメッセ群馬） 優秀演題賞
・2025年度 公益信託 日本白血病研究基金 一般研究賞
研究費獲得状況
科研費
-
多発性骨髄腫の髄外病変形成機構の解明と治療標的の探索：一細胞・空間オミクスで迫る
日本学術振興会 科学研究費助成事業 基盤研究(C) 2025年4月 - 2027年3月 - 多発性骨髄腫の不均一性を考慮した経時的一細胞RNA解析による薬剤耐性遺伝子の同定
日本学術振興会 科学研究費助成事業 基盤研究(C) 2022年4月 - 2025年3月
民間助成金
- 2025年度 公益信託 日本白血病研究基金 一般研究賞
- 日本血液学会 研究助成 2025年4月 - 2026年3月
- 武田科学振興財団 2024年度 医学系研究助成 2024年9月 - 2029年3月
- 貝原守一医学振興財団 令和 5 年度 研究助成金 2024年4月 - 2027年3月
- 日本血液学会 研究助成 2024年4月 - 2025年3月
- 日本血液学会 研究助成 2023年4月 - 2024年3月
- 日本応用酵素協会 成人病の病因・病態の解明に関する研究助成 (TMFC) 2022年4月 - 2025年3月
- ふくおか公衆衛生推進機構 がん研究助成金 2022年4月 - 2023年3月
- 日本血液学会 研究助成 2022年4月 - 2023年3月
- 臨床医学振興財団 医学研究資金助成 2022年1月 - 2024年3月
- 臨床研究奨励基金 臨床研究助成 2021年11月 - 2024年3月
- 大和証券ヘルス財団 調査研究助成 2021年10月 - 2022年10月
- 九州大学 ＱＲプログラム わかばチャレンジ 2021年4月 - 2022年3月
- 九州大学 QRプログラム わかばチャレンジ 2020年10月 - 2021年3月
原著論文
Haji S, Ogawa Y.
TET3-overexpressing macrophages are a unifying pathogenic feature with therapeutic potential in chronic inflammatory diseases.
Fujioka E, Kiyasu J, Choi L, Yagi Y, Sawabe T, Oyama M, Hoashi K, Tsuda M, Takamatsu A, Haji S, Yufu Y, Suehiro Y, Shiratsuchi M.
Efficacy and Safety of Rituximab plus Modified EPOCH (Etoposide, Vincristine, Doxorubicin, Carboplatin, and Prednisolone) for Transplant-ineligible Relapsed/Refractory Diffuse Large B-cell Lymphoma.
Intern Med. 2025 Apr 12. doi: 10.2169/internalmedicine.5175-24. Epub ahead of print.
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Cell. 2024 Oct 17;187(21):6071-6087.
Haji S, Shiratsuchi M, Takamatsu A, Tsuda M, Muta H, Masuda T, Nakashima Y, Ogawa Y.
Endothelial function testing before conditioning therapy is useful for predicting transplant-related complications after allogeneic hematopoietic cell transplantation.
International journal of hematology. 2023 Mar;117(3):438-445.
Haji S, Ito T, Guenther C, Nakano M, Shimizu T, Mori D, Chiba Y, Tanaka M, Mishra SK, Willment JA, Brown GD, Nagae M, Yamasaki S.
Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2.
elife. 2022 Dec 8:11:e83037.
Masuda T, Haji S (equally contributed), Nakashima Y, Tsuda M, Kimura D, Takamatsu A, Iwahashi N, Umakoshi H, Shiratsuchi M, Kikutake C, Suyama M, Ohkawa Y, Ogawa Y.
Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing
iScience. 2022 Jul 19;25(8):104781.
Tsuda M, Hirata A, Tokunaga S, Masuda T, Haji S, Kimura D, Nojiri C, Nakashima Y, Shiratsuchi M, Kato K, Miyamoto T, Akashi K, Nakashima N, Ogawa Y.
Rapid decrease in eGFR with concomitant use of tyrosine kinase inhibitors and renin-aldosterone-angiotensin system inhibitors in patients with chronic myelogenous leukemia
Int J Hematol. 2022 Dec;116(6):863-870.
Takamatsu A, Nakashima Y, Haji S, Tsuda M, Masuda T, Kimura D, Shitatsuchi M, Ogawa Y.
Circulating endothelial cells and endothelial progenitor cells as potential predictors of acute GVHD after allogeneic hematopoietic stem cell transplantation.
Eur J Haematol. 2022 Aug;109(2):146-153.
Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker B, Timmer MS, Smith DGM, Williams SJ, Bamba T, Miyamoto T, Arita M, Appelmelk BJ, Yamasaki S.
Helicobacter metabolites exacerbate gastritis through C-type lectin receptors.
J Exp Med. 2021 Jan 4;218(1):e20200815.
Narazaki T, Shiratsuchi M, Matsushima T, Tsuda M, Tsukamoto Y, Muta H, Masuda T, Kimura D, Takamatsu A, Yamamoto H, Oda Y, Miyoshi H, Ohshima K, Matsuda Y, Sakamoto R, Nakashima Y, Ogawa Y.
Clinico-pathological characteristics of primary adrenal lymphomas – potential efficacy of autologous stem cell transplantation.
Leukemia & Lymphoma. 2020 Jun;61(6):1516-1518. doi: 10.1080/10428194.2020.1725507.
Narazaki T, Nakashima Y, Tsukamoto Y, Nishida R, Tsuda M, Muta H, Kimura D, Masuda T, Takamatsu A, Kohashi K, Murakami D, Shiratsuchi M, Ogawa Y.
Schizophyllum commune sinusitis after allogeneic bone marrow transplantation for myelodysplastic syndrome: A case report and literature review.
Transpl Infect Dis. 2020 Feb;22(1):e13205.
Narazaki T, Shiratsuchi M, Tsuda M, Tsukamoto Y, Muta H, Masuda T, Kimura D, Takamatsu A, Nakanishi R, Oki E, Fujiwara M, Oda Y, Nakashima Y, Ogawa Y.
Intestinal Behçet's Disease with Primary Myelofibrosis Involving Trisomy 8.
Acta Haematol. 2019 Jul 10:1-4.
Narazaki T, Nakashima Y, Tsukamoto Y, Tsuda M, Masuda T, Kimura D, Takamatsu A, Ohshima K, Shiratsuchi M, Ogawa Y.
Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma.
Int J Hematol. 2019 Sep;110(3):375-380.
Narazaki T, Haji S, Nakashima Y, Tsukamoto Y, Tsuda M, Takamatsu A, Ohno H, Matsushima T, Matsumoto T, Nogami K, Shima M, Shiratsuchi M, Ogawa Y.
Acquired hemophilia A associated with autoimmune pancreatitis with serum IgG4 elevation.
Int J Hematol. 2018 Sep;108(3):335-338.
Tsuda M, Shiratsuchi M, Nakashima Y, Ikeda M, Muta H, Narazaki T, Masuda T, Kimura D, Takamatsu A, Matsumoto M, Fujimura Y, Kokame K, Matsushima T and Ogawa Y.
Upshaw-Schulman syndrome diagnosed during pregnancy complicated by reversible cerebral vasoconstriction syndrome.
Transfus Apher Sci. 2018; 57: 790-792.
Xiong P, Shiratsuchi M, Matsushima T, Liao J, Tanaka E, Nakashima Y, Takayanagi R, Ogawa Y. Regulation of expression and trafficking of perforin-2 by LPS and TNF-α.
Cell Immunol. 2017 Oct;320:1-10.
Haji S, Shiratsuchi M, Matsushima T, Takamatsu A, Tsuda M, Tsukamoto Y, Tanaka E, Ohno H, Fujioka E, Ishikawa Y, Imadome K, Ogawa Y.
Achievement of disease control with donor-derived EB virus-specific cytotoxic T cells after allogeneic peripheral blood stem cell transplantation for aggressive NK-cell leukemia.
Int J Hematol. 105:540-544, 2017
Haji S, Kiyasu J, Choi I, Suehiro Y, Toyoda K, Tsuda M, Takamatsu A, Nakashima Y, Miyoshi H, Shiratsuchi M, Yamasaki S, Uike N, Abe Y.
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma.
Bone Marrow Transplant. 51:432-434, 2015
McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, Kirsner RS, Russell DG, Podack ER.
Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.
elife 4:pii: e06508, 2015
Kiyasu J, Miyoshi H, Hirata A, Arakawa F, Ichikawa A, Niino D, Sugita Y, Yufu Y, Choi I, Abe Y, Uike N, Nagafuji K, Okamura T, Akashi K, Takayanagi R, Shiratsuchi M, Oshima K.
Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma.
Blood. 126(19): 2193-2201, 2015
Tsuda M, Nakashima Y, Ikeda M, Shimada S, Nomura M, Matsushima T, Takahashi S, Aishima S, Oda Y, Shiratsuchi M, Takayanagi R.
Intravascular Large B-Cell Lymphoma Complicated by Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis that was Successfully Treated with Rituximab-Containing Chemotherapy.
J Clin Exp Hematop. 55(1): 39-43, 2015
Nakashima Y, Shiratsuchi M, Abe I, Matsuda Y, Miyata N, Ohno H, Ikeda M, Matsushima T, Nomura M, Takayanagi R.
Pituitary and adrenal involvement in diffuse large B-cell lymphoma, with recovery of their function after chemotherapy.
BMC Endocr Disord. 13: 45, 2013
Sada E, Abe Y, Ohba R, Tachikawa Y, Nagasawa E, Shiratsuchi M, Takayanagi R.
Vitamin K2 modulates differentiation and apoptosis of bith myeloid and erythroid lineages.
Eur J Haematol. 85: 538-548, 2010
Ohtsuka R, Abe Y, Sada E, Kiyasu J, Ashikari A, Shiratsuchi M, Nishimura J, Takayanagi R, Ohshima K.
Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?
Intern Med. 48: 471-474, 2009
Abe Y, Ito T, Baba E, Nagafuji K, Kawabe K, Choi I, Arita Y, Miyamoto T, Teshima T, Nakano S, Harada M.
Nonmyeloablative allogeneic hematopoietic stem cell transplantation as immunotherapy for pancreatic cancer.
Pancreas. 38: 815-819, 2009
Miyashita K, Fujii K, Yamada Y, Hattori H, Taguchi K, Yamanaka T, Yoshida MA, Okamura J, Oda S, Muta K, Nawata H, Takayanagi R, Uike N.
Frequent microsatellite instability in non-Hodgkin lymphomas irresponsive to chemotherapy.
Leukemia Research. 32: 1183-1195, 2008
Sarakul O, Vattanaviboon P, Wilairat P, Fucharoen S, Abe Y, Muta K.
Inhibition of alpha-globin gene expression by RNAi.
Biochem Biophys Res Commun. 369: 935-938, 2008
Masaki S, Ohtsuka R, Abe Y, Muta K, Umemura T.
Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis.
Biochem Biophys Res Commun. 364: 509-514, 2007
Ohtsuka R, Abe Y, Fujii T, Yamamoto M, Nishimura J, Takayanagi R, Muta K.
Mortalin is a novel mediator of erythropoietin signaling.
Eur J Haematol. 79: 114-125, 2007
Tachikawa Y, Matsushima T, Abe Y, Sakano S, Yamamoto M, Nishimura J, Nawata H, Takayanagi R, Muta K.
Pivotal role of Notch signaling in regulation of erythroid maturation and proliferation.
Eur J Haematol. 77: 273-281, 2006
Nakashima Y, Tagawa H, Suzuki R, Karnan S, Karube K, Ohshima K, Muta K, Nawata H, Morishima Y, Nakamura S, Seto M.
Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type.
Genes Chromosomes Cancer. 44: 247-255, 2005
Nagasawa E, Abe Y, Nishimura J, Yanase T, Nawata H, Muta K.
Pivotal role of peroxisome proliferator-activated receptor gamma (PPARγ) in regulation of erythroid progenitor cell proliferation and differentiation.
Exp Hematol. 33: 857-864, 2005
Sae-Ung N, Matsushima T, Choi I, Abe Y, Winichagoon P, Fucharoen S, Nawata H, Muta K.
Role of NF-κB in regulation of apoptosis of erythroid progenitor cells.
Eur J Haematol. 74: 315-323, 2005
Zhang M, Abe Y, Matsushima T, Nishimura J, Nawata H, Muta K.
Selective cyclooxygenase 2 inhibitor NS-398 induces apoptosis in myeloma cells via a Bcl-2 independent pathway.
Leuk Lymphoma. 46: 425-433, 2005
Muta K, Ohshima K, Abe Y, Uike N, Choi I, Matsushima T, Nishimura J, Kikuchi M, Nakashima M, Watanabe T, Nawata H.
Expression of human tumor-associated antigen RCAS1 in adult T-cell leukemia/lymphoma.
Int J Hematol. 79: 340-344, 2004
Shiokawa S, Matsushima T, Choi I, Abe Y, Shiratsuchi M, Suehiro Y, Muta K, Ohshima K, Nishimura J.
Re-entry of tumor B cells into the cycle of somatic mutation and isotype switching in follicular lymphoma.
Br J Haematol. 120: 492-495, 2003
Abe Y, Ohshima K, Nakashima M, Hara K, Matsushima T, Choi I, Nishimura J, Kikuchi M, Nawata H, Watanabe T, Muta K.
Expression of apoptosis-associated protein RCAS1 in macrophages of histiocytic necrotizing lymphadenitis.
Int J Hematol. 77: 359-363, 2003
Minami R, Muta K, Umemura T, Motomura S, Abe Y, Nishimura J, Nawata H.
p16(INK4a) induces differentiation and apoptosis in erythroid lineage cells.
Exp Hematol. 31: 355-362, 2003
Abe Y, Choi I, Matsushima T, Nishimura J, Inaba S, Nawata H, Muta K.
Hemophagocytic syndrome: a rare complication of allogeneic nonmyeloablative hematopoietic stem cell transplantation.
Bone Marrow Transplant. 29: 799-801, 2002
Shiratsuchi M, Muta K, Abe Y, Motomura S, Taguchi F, Takatsuki H, Uike N, Umemura T, Nawata H, Nishimura J.
Clinical significance of telomerase activity in multiple myeloma.
Cancer. 94: 2232-2238, 2002
Matsushima T, Nakashima M, Oshima K, Abe Y, Nishimura J, Nawata H, Watanabe T, Muta K.
Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells.
Blood. 98: 313-321, 2001
Choi I, Muta K, Wickrema A, Krantz SB, Nishimura J, Nawata H.
Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin.
Blood. 95: 3742-3749, 2000
TET3-overexpressing macrophages are a unifying pathogenic feature with therapeutic potential in chronic inflammatory diseases.
J Clin Invest. 2025;135(21):e198802. https://doi.org/10.1172/JCI198802.
Tsukamoto Y, Kawamura A, Yurtsever A, Suzuki H, Nichole Marcela Rojas-Chaverra, Sato H, Ino D, Ichikawa T, Weilin Wei, Haji S, Dominic Chih-Cheng Voon, Matsumoto A, Matsumoto K, Takahashi H, Kodera N, Fukuma T, Ogawa Y, Nishiyama M, Sakai K.
Condensation-dependent interactome of a chromatin remodeler underlies tumor suppressor activities.
Nat Commun. 16(1):9599 (2025). https://doi.org/10.1038/s41467-025-64655-w
Fujioka E, Kiyasu J, Choi L, Yagi Y, Sawabe T, Oyama M, Hoashi K, Tsuda M, Takamatsu A, Haji S, Yufu Y, Suehiro Y, Shiratsuchi M.
Efficacy and Safety of Rituximab plus Modified EPOCH (Etoposide, Vincristine, Doxorubicin, Carboplatin, and Prednisolone) for Transplant-ineligible Relapsed/Refractory Diffuse Large B-cell Lymphoma.
Intern Med. 2025 Apr 12. doi: 10.2169/internalmedicine.5175-24. Epub ahead of print.
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Cell. 2024 Oct 17;187(21):6071-6087.
Haji S, Shiratsuchi M, Takamatsu A, Tsuda M, Muta H, Masuda T, Nakashima Y, Ogawa Y.
Endothelial function testing before conditioning therapy is useful for predicting transplant-related complications after allogeneic hematopoietic cell transplantation.
International journal of hematology. 2023 Mar;117(3):438-445.
Haji S, Ito T, Guenther C, Nakano M, Shimizu T, Mori D, Chiba Y, Tanaka M, Mishra SK, Willment JA, Brown GD, Nagae M, Yamasaki S.
Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2.
elife. 2022 Dec 8:11:e83037.
Masuda T, Haji S (equally contributed), Nakashima Y, Tsuda M, Kimura D, Takamatsu A, Iwahashi N, Umakoshi H, Shiratsuchi M, Kikutake C, Suyama M, Ohkawa Y, Ogawa Y.
Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing
iScience. 2022 Jul 19;25(8):104781.
Tsuda M, Hirata A, Tokunaga S, Masuda T, Haji S, Kimura D, Nojiri C, Nakashima Y, Shiratsuchi M, Kato K, Miyamoto T, Akashi K, Nakashima N, Ogawa Y.
Rapid decrease in eGFR with concomitant use of tyrosine kinase inhibitors and renin-aldosterone-angiotensin system inhibitors in patients with chronic myelogenous leukemia
Int J Hematol. 2022 Dec;116(6):863-870.
Takamatsu A, Nakashima Y, Haji S, Tsuda M, Masuda T, Kimura D, Shitatsuchi M, Ogawa Y.
Circulating endothelial cells and endothelial progenitor cells as potential predictors of acute GVHD after allogeneic hematopoietic stem cell transplantation.
Eur J Haematol. 2022 Aug;109(2):146-153.
Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker B, Timmer MS, Smith DGM, Williams SJ, Bamba T, Miyamoto T, Arita M, Appelmelk BJ, Yamasaki S.
Helicobacter metabolites exacerbate gastritis through C-type lectin receptors.
J Exp Med. 2021 Jan 4;218(1):e20200815.
Narazaki T, Shiratsuchi M, Matsushima T, Tsuda M, Tsukamoto Y, Muta H, Masuda T, Kimura D, Takamatsu A, Yamamoto H, Oda Y, Miyoshi H, Ohshima K, Matsuda Y, Sakamoto R, Nakashima Y, Ogawa Y.
Clinico-pathological characteristics of primary adrenal lymphomas – potential efficacy of autologous stem cell transplantation.
Leukemia & Lymphoma. 2020 Jun;61(6):1516-1518. doi: 10.1080/10428194.2020.1725507.
Narazaki T, Nakashima Y, Tsukamoto Y, Nishida R, Tsuda M, Muta H, Kimura D, Masuda T, Takamatsu A, Kohashi K, Murakami D, Shiratsuchi M, Ogawa Y.
Schizophyllum commune sinusitis after allogeneic bone marrow transplantation for myelodysplastic syndrome: A case report and literature review.
Transpl Infect Dis. 2020 Feb;22(1):e13205.
Narazaki T, Shiratsuchi M, Tsuda M, Tsukamoto Y, Muta H, Masuda T, Kimura D, Takamatsu A, Nakanishi R, Oki E, Fujiwara M, Oda Y, Nakashima Y, Ogawa Y.
Intestinal Behçet's Disease with Primary Myelofibrosis Involving Trisomy 8.
Acta Haematol. 2019 Jul 10:1-4.
Narazaki T, Nakashima Y, Tsukamoto Y, Tsuda M, Masuda T, Kimura D, Takamatsu A, Ohshima K, Shiratsuchi M, Ogawa Y.
Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma.
Int J Hematol. 2019 Sep;110(3):375-380.
Narazaki T, Haji S, Nakashima Y, Tsukamoto Y, Tsuda M, Takamatsu A, Ohno H, Matsushima T, Matsumoto T, Nogami K, Shima M, Shiratsuchi M, Ogawa Y.
Acquired hemophilia A associated with autoimmune pancreatitis with serum IgG4 elevation.
Int J Hematol. 2018 Sep;108(3):335-338.
Tsuda M, Shiratsuchi M, Nakashima Y, Ikeda M, Muta H, Narazaki T, Masuda T, Kimura D, Takamatsu A, Matsumoto M, Fujimura Y, Kokame K, Matsushima T and Ogawa Y.
Upshaw-Schulman syndrome diagnosed during pregnancy complicated by reversible cerebral vasoconstriction syndrome.
Transfus Apher Sci. 2018; 57: 790-792.
Xiong P, Shiratsuchi M, Matsushima T, Liao J, Tanaka E, Nakashima Y, Takayanagi R, Ogawa Y. Regulation of expression and trafficking of perforin-2 by LPS and TNF-α.
Cell Immunol. 2017 Oct;320:1-10.
Haji S, Shiratsuchi M, Matsushima T, Takamatsu A, Tsuda M, Tsukamoto Y, Tanaka E, Ohno H, Fujioka E, Ishikawa Y, Imadome K, Ogawa Y.
Achievement of disease control with donor-derived EB virus-specific cytotoxic T cells after allogeneic peripheral blood stem cell transplantation for aggressive NK-cell leukemia.
Int J Hematol. 105:540-544, 2017
Haji S, Kiyasu J, Choi I, Suehiro Y, Toyoda K, Tsuda M, Takamatsu A, Nakashima Y, Miyoshi H, Shiratsuchi M, Yamasaki S, Uike N, Abe Y.
Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma.
Bone Marrow Transplant. 51:432-434, 2015
McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, Kirsner RS, Russell DG, Podack ER.
Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.
elife 4:pii: e06508, 2015
Kiyasu J, Miyoshi H, Hirata A, Arakawa F, Ichikawa A, Niino D, Sugita Y, Yufu Y, Choi I, Abe Y, Uike N, Nagafuji K, Okamura T, Akashi K, Takayanagi R, Shiratsuchi M, Oshima K.
Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma.
Blood. 126(19): 2193-2201, 2015
Tsuda M, Nakashima Y, Ikeda M, Shimada S, Nomura M, Matsushima T, Takahashi S, Aishima S, Oda Y, Shiratsuchi M, Takayanagi R.
Intravascular Large B-Cell Lymphoma Complicated by Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis that was Successfully Treated with Rituximab-Containing Chemotherapy.
J Clin Exp Hematop. 55(1): 39-43, 2015
Nakashima Y, Shiratsuchi M, Abe I, Matsuda Y, Miyata N, Ohno H, Ikeda M, Matsushima T, Nomura M, Takayanagi R.
Pituitary and adrenal involvement in diffuse large B-cell lymphoma, with recovery of their function after chemotherapy.
BMC Endocr Disord. 13: 45, 2013
Sada E, Abe Y, Ohba R, Tachikawa Y, Nagasawa E, Shiratsuchi M, Takayanagi R.
Vitamin K2 modulates differentiation and apoptosis of bith myeloid and erythroid lineages.
Eur J Haematol. 85: 538-548, 2010
Ohtsuka R, Abe Y, Sada E, Kiyasu J, Ashikari A, Shiratsuchi M, Nishimura J, Takayanagi R, Ohshima K.
Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?
Intern Med. 48: 471-474, 2009
Abe Y, Ito T, Baba E, Nagafuji K, Kawabe K, Choi I, Arita Y, Miyamoto T, Teshima T, Nakano S, Harada M.
Nonmyeloablative allogeneic hematopoietic stem cell transplantation as immunotherapy for pancreatic cancer.
Pancreas. 38: 815-819, 2009
Miyashita K, Fujii K, Yamada Y, Hattori H, Taguchi K, Yamanaka T, Yoshida MA, Okamura J, Oda S, Muta K, Nawata H, Takayanagi R, Uike N.
Frequent microsatellite instability in non-Hodgkin lymphomas irresponsive to chemotherapy.
Leukemia Research. 32: 1183-1195, 2008
Sarakul O, Vattanaviboon P, Wilairat P, Fucharoen S, Abe Y, Muta K.
Inhibition of alpha-globin gene expression by RNAi.
Biochem Biophys Res Commun. 369: 935-938, 2008
Masaki S, Ohtsuka R, Abe Y, Muta K, Umemura T.
Expression patterns of microRNAs 155 and 451 during normal human erythropoiesis.
Biochem Biophys Res Commun. 364: 509-514, 2007
Ohtsuka R, Abe Y, Fujii T, Yamamoto M, Nishimura J, Takayanagi R, Muta K.
Mortalin is a novel mediator of erythropoietin signaling.
Eur J Haematol. 79: 114-125, 2007
Tachikawa Y, Matsushima T, Abe Y, Sakano S, Yamamoto M, Nishimura J, Nawata H, Takayanagi R, Muta K.
Pivotal role of Notch signaling in regulation of erythroid maturation and proliferation.
Eur J Haematol. 77: 273-281, 2006
Nakashima Y, Tagawa H, Suzuki R, Karnan S, Karube K, Ohshima K, Muta K, Nawata H, Morishima Y, Nakamura S, Seto M.
Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type.
Genes Chromosomes Cancer. 44: 247-255, 2005
Nagasawa E, Abe Y, Nishimura J, Yanase T, Nawata H, Muta K.
Pivotal role of peroxisome proliferator-activated receptor gamma (PPARγ) in regulation of erythroid progenitor cell proliferation and differentiation.
Exp Hematol. 33: 857-864, 2005
Sae-Ung N, Matsushima T, Choi I, Abe Y, Winichagoon P, Fucharoen S, Nawata H, Muta K.
Role of NF-κB in regulation of apoptosis of erythroid progenitor cells.
Eur J Haematol. 74: 315-323, 2005
Zhang M, Abe Y, Matsushima T, Nishimura J, Nawata H, Muta K.
Selective cyclooxygenase 2 inhibitor NS-398 induces apoptosis in myeloma cells via a Bcl-2 independent pathway.
Leuk Lymphoma. 46: 425-433, 2005
Muta K, Ohshima K, Abe Y, Uike N, Choi I, Matsushima T, Nishimura J, Kikuchi M, Nakashima M, Watanabe T, Nawata H.
Expression of human tumor-associated antigen RCAS1 in adult T-cell leukemia/lymphoma.
Int J Hematol. 79: 340-344, 2004
Shiokawa S, Matsushima T, Choi I, Abe Y, Shiratsuchi M, Suehiro Y, Muta K, Ohshima K, Nishimura J.
Re-entry of tumor B cells into the cycle of somatic mutation and isotype switching in follicular lymphoma.
Br J Haematol. 120: 492-495, 2003
Abe Y, Ohshima K, Nakashima M, Hara K, Matsushima T, Choi I, Nishimura J, Kikuchi M, Nawata H, Watanabe T, Muta K.
Expression of apoptosis-associated protein RCAS1 in macrophages of histiocytic necrotizing lymphadenitis.
Int J Hematol. 77: 359-363, 2003
Minami R, Muta K, Umemura T, Motomura S, Abe Y, Nishimura J, Nawata H.
p16(INK4a) induces differentiation and apoptosis in erythroid lineage cells.
Exp Hematol. 31: 355-362, 2003
Abe Y, Choi I, Matsushima T, Nishimura J, Inaba S, Nawata H, Muta K.
Hemophagocytic syndrome: a rare complication of allogeneic nonmyeloablative hematopoietic stem cell transplantation.
Bone Marrow Transplant. 29: 799-801, 2002
Shiratsuchi M, Muta K, Abe Y, Motomura S, Taguchi F, Takatsuki H, Uike N, Umemura T, Nawata H, Nishimura J.
Clinical significance of telomerase activity in multiple myeloma.
Cancer. 94: 2232-2238, 2002
Matsushima T, Nakashima M, Oshima K, Abe Y, Nishimura J, Nawata H, Watanabe T, Muta K.
Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells.
Blood. 98: 313-321, 2001
Choi I, Muta K, Wickrema A, Krantz SB, Nishimura J, Nawata H.
Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin.
Blood. 95: 3742-3749, 2000
著書・総説
西村直矢, 土師正二郎, 本園千尋
結核菌を認識するあらたなC型レクチン受容体
医学のあゆみ Volume 261, Issue 13 (2017), 1243 - 1244
Podack ER, Deyev V, Shiratsuchi M.
Pore formers of the immune system.
Adv Exp Med Biol. 598: 325-341, 2007
白土基明
ウイルス感染と血球貪食症候群
血液フロンティア 2013;23:61-68.
安部康信, 大島孝一.
EBV関連リンパ腫をどう理解するか
症例検討を通して学ぶ悪性リンパ腫診療の実際－リンフォーマ井戸端会議から学んだこと－:
メディカルレビュー社; 97-102, 2010
牟田耕一郎, 安部康信.
サラセミア
専門医のための薬物療法Q＆A:
中外医学社; 92-98, 2007
白土基明, 牟田耕一郎.
先天性疾患における輸血依存性鉄過剰症の病態
Iron Overloadと鉄キレート療法:
メディカルレビュー社; 117-122, 2007
結核菌を認識するあらたなC型レクチン受容体
医学のあゆみ Volume 261, Issue 13 (2017), 1243 - 1244
Podack ER, Deyev V, Shiratsuchi M.
Pore formers of the immune system.
Adv Exp Med Biol. 598: 325-341, 2007
白土基明
ウイルス感染と血球貪食症候群
血液フロンティア 2013;23:61-68.
安部康信, 大島孝一.
EBV関連リンパ腫をどう理解するか
症例検討を通して学ぶ悪性リンパ腫診療の実際－リンフォーマ井戸端会議から学んだこと－:
メディカルレビュー社; 97-102, 2010
牟田耕一郎, 安部康信.
サラセミア
専門医のための薬物療法Q＆A:
中外医学社; 92-98, 2007
白土基明, 牟田耕一郎.
先天性疾患における輸血依存性鉄過剰症の病態
Iron Overloadと鉄キレート療法:
メディカルレビュー社; 117-122, 2007